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Growth hormone plays a direct role in protein synthesis and musclefiber maintenance, which is why clinicians are evaluating whether sermorelin, agrowth hormone-releasing peptide, may support better body composition outcomeswhen used alongside GLP-1 medications

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Weight loss occurs gradually over months and eventually plateaus

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MK-677 (Ibutamoren): MK-677 is an oral GH secretagogue with a long half-life

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Acknowledgements This work was supported by NSERC grants 551669-152199-2004 to E.E.M., 2018-06545 to K.A.P., and RGPIN/04468-2020 to M.E.H

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