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Tracer studies employing 13C-labeled lactate have demonstrated robust incorporation of lactate-derived carbon into TCA intermediates across a wide array of tissues, encompassing both healthy and malignant cells (31,32)
Regarding treatment strategies, it is suggested that the marked decrease in GPx1 expression may be the major mechanism of tumor sensitization to anthracyclines [93] and that GPx1 can partially inhibit doxorubicin-induced cell death-related signaling in breast cancer by interfering with the activation of the sphingomyelin-ceramide pathway [85]
Al-Kindi KM, Alkharusi A, Alshukaili D, Al Nasiri N, Al-Awadhi T, Charabi Y, et al
La fruta por la noche se convierte en grasa. Falso
Newman, A
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