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7 (download XLSX Source data for Extended Data Fig

Consequently, it remains a highly relevant compound across obesity and energy homeostasis research disciplines

Moreover, it inhibits glucagon release from the cells of the pancreas and promotes slow stomach emptying, hence giving the feeling of fullness and reduces body weight (12)

Note also the decoupling between exposure and effect: although sermorelin was cleared within minutes after IV injection, GH concentrations stayed elevated for roughly three hours [7]