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In mice, TAS2R131 has been implicated in xenobiotic defense by promoting mucus production in the colon (80)
Compounded formulations of GLP-1s are not reviewed by the FDA for safety, efficacy, or quality
Despite demonstrating robust glycemic efficacy, both agents were eventually discontinued due to distinct tolerability and safety concerns, diverging in severity and clinical implications
Yet people looking to take a GLP-1 RA (or glucagon-like peptide 1 receptor agonist) dont have to see a specialist or even their primary care physician to get their hands on these drugs
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