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Non-obstructive azoospermia refers to the absence of sperm within the ejaculate fluid due to a testicular production cause
For example, INT-777 and MN6, TGR5 selective agonists, stimulated GLP-1 secretion and improved insulin sensitivity in diet-induced obesity (DIO) mice [180, 181]
doi:10.1111/jpi.12026
Sources: Gorgojo-Martnez JJ, Mezquita-Raya P, Carretero-Gmez J, et al
These drugs mimic the action of naturally occurring GLP-1, an incretin hormone released by the intestine in response to food intake
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