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Presented for research literature review only Naash MI et al
a non-GLP-1 agonist show that overall, thyroid cancer is increased in people who take GLP-1s
When the peptide binds with copper ions, it forms a biologically active complex capable of transporting copper into tissues and cells
GLP-1 usage has surged, but many stop treatment prematurely While high costs may play a role in discontinuation, cases where side effects prompt patients to stop treatment should raise concerns for plan sponsors about the significant upfront investment required to initiate these therapies
Hyperglycemia increases notch activity in vitro and vivo, and consistent activation of notch results in impaired GSIS and blocks maturation of cells, which may be a result of degradation of MAFA due to the blockage of its binding to kat2b
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