Intravenous NAC is the standard of care, providing cysteine to regenerate glutathione (Smilkstein et al., N Engl J Med, 1988) [32]
In Alzheimers disease models, it also upregulates endogenous antioxidative enzymes such as SOD and catalase, mitigating amyloid--induced oxidative injury ( Riboflavin further modulates redox-sensitive transcription factors including Nrf2 and AP-1, thereby inducing downstream antioxidant genes like NQO1, GCLC, and HO-1
The body produces its own glutathione but poor diet, stress, pollution, toxins, and aging may deplete the bodys reserves
V., Hasegawa, P
Avoid Smoking and Alcohol: These can deplete antioxidants in the body and reduce the effectiveness of glutathione