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When to Call Your Provider Most first-week side effects are mild and manageable, but there are a few things that warrant a call to your healthcare provider: persistent vomiting that prevents you from keeping food or fluids down, severe abdominal pain (especially in the upper abdomen that radiates to your back), signs of an allergic reaction like swelling, difficulty breathing, or a rash, or any symptom that feels unusual or concerning to you

Avoid Extreme Temperatures: Avoid exposing the pen to extreme heat or cold, as this can affect the medications stability

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