Because at the end of the day, this isnt just about numbers or hormones
Notwithstanding, previous studies have documented beneficial effects of the activation of estrogen receptors in diet-induced obese females, by reducing body weight and fat accumulation and improving leptin resistance at central level 53,54
Researchers running high-dose protocols that deplete vials quickly face less stability concern, but those on lower doses like 1mg or 2mg may find that a single vial lasts close to the stability window, making careful date tracking essential
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The CCA for the remaining meta-analyses was 20.83%, indicating a very high level of overlap