Accumulating extra-synaptic glutamate due to the over-activation of microglia promotes aberrant synaptic signaling in PD and other neurodegenerative brain diseases (Iovino et al
In the first stage, inflammatory cytokines disrupt the structural integrity of the BBB, leading to the extravasation of plasma proteins (56)
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These recommendations align with the ergogenic profile of L-carnitine observed in our study and may be especially useful during peak phases of periodization or race preparation
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