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The speculative domain includes specific human dosing recommendations, which are extrapolated from animal studies and scaled by allometric principles rather than derived from human pharmacokinetic data
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10.1038/s12276-022-00739-7 18 HuJ.LiuW.ZouY.JiaoC.ZhuJ.XuQ.et al (2024)
Cortisol can rise at the wrong times, and that can keep the body on alert
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