The pro-inflammatory cytokines (IL-6 and TNF-) released during the pathophysiology of NAFLD are mainly derived from macrophages (23)
These, for example, include prodrug strategies, as seen in the case of OTC, which was designed to have improved bioavailability and stability (it is thought of being converted to cysteine intracellularly, which is then used for GSH synthesis) or NAC amide that has improved lipophilicity and cell permeability
Research shows it may help stabilize the mucosal lining, reduce gut inflammation, and support recovery from conditions like gastric ulcers and gut barrier disruption
Progress Over Time Weight loss typically occurs gradually as the body adjusts to treatment and new eating patterns
However, some studies show only small declines, while others have found more promising ones, so more research is needed