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Semaglutide trials (STEP 14 series) documented nausea in roughly 2025% of patients, suggesting a modest numerical difference
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Results from subgroup analyses of the Evaluate Renal Function with Semaglutide Once Weekly (FLOW), the Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity (SELECT), the Effect of Semaglutide 2.4 mg Once Weekly on Function and Symptoms in Subjects with Obesity-related Heart Failure with Preserved Ejection Fraction (STEP-HFpEF), and the Semaglutide Treatment Effect in People with Obesity and Heart Failure with Preserved Ejection Fraction and Diabetes Mellitus (STEP-HFpEF DM) trials showed that semaglutide tended to be more effective in younger patients, those with higher BMI, higher GFR, and lower HbA1c levels 22,23,24
FUNDING This study was also supported in part by a research grant from Eulji University (2021EMBRISN0001)
It is derived from a partial sequence of the Body Protection Compound (BPC) protein, which is naturally isolated from gastric juice in the human digestive tract
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