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During stimulation with AGEs-BSA, impaired lysosomal function and blocked autophagic flux were observed, as evidenced by increased protein levels of LC3-II and P62, alongside decreased expression of CTSD, CTSB, LAMP1 and LAMP2

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10.1021/acsanm.9b02603 62 ShangW.ZengC.DuY.HuiH.LiangX.ChiC.et al (2017)

Users may need to remain on semaglutide long-term to maintain their weight loss , leading to ongoing issues regarding cost and availability

Containing semaglutide, Ozempic acts similarly to the GLP-1 hormone, helping to control blood sugar levels