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Hormones such as ghrelin (the "hunger hormone") may increase, while leptin levels decline with fat mass reduction
Sermorelin & Ipamorelin Blend and Skeletal Muscles In the aforementioned 16-week study, researchers proposed that Sermorelin may increase lean body mass by approximately 2.78lbs (1.26kg)
doi: 10.1016/j.ajog.2018.11.1098
The general consensus is that a day early is fine, while consistently shortening the interval between doses is not recommended as it increases side effect risk
Any assertion to the contrary is not supported by evidence It IS fair to say that there is no clear evidence of harm in a relatively data free zone in humans, and that there is a plausible argument for benefit based upon in vitro and animal studies as well as mechanism of action - particularly with BPC
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