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Complementary mechanisms

Americans are increasingly seeking innovative therapies for aging, chronic pain and longevityoften faster than science can provide definitive answers

REDEFINE 1 (NCT05567796), REDEFINE 2 (NCT05394519), REDEFINE 3 (NCT05669755), REDEFINE 4 (NCT06131437), REDEFINE 11 (NCT07011667), REIMAGINE 2 (NCT06065540)

In published preclinical work, inhibiting NNMT is associated with elevated intracellular NAD and SAM, reduced lipogenesis and smaller adipocytes in cell and diet-induced-obese rodent models, and is studied in the context of insulin sensitivity and muscle function