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Obesity and respiratory diseases
The dog CluGST A3-3 protein, differing in only four of the residues forming the substrate-binding site in HsaGST A3-3 and EcaGST A3-3, displays a specific activity with 5-AD of only 1.1 mol min 1 mg 1 , 200-fold lower than the specific activities of the human and equine enzymes (A
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However, acetyl-L-carnitine does not seem to work when injected into the muscle
We demonstrate that this effect of a GLP-1R agonist was translationally relevant in human islets through application of a single-cell RNA-Seq (scRNA-Seq) technology, droplet-assisted RNA targeting by single-cell sequencing (DART-Seq) (23), a high-sensitivity scRNA-Seq approach
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