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Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease
Apoptosis was detected using an Annexin V-FITC/PI Apoptosis Detection Kit
All experiments were conducted using male Kunming strain mice weighing 1822 grams
Humans express three ADP/ATP carriers which are all members of the SLC family of membrane transporters, specifically SLA25A4, SLC25A5, and SLC25A6
Wilkins et al., 2012), mainly in kidney and liver, and tricarboxylate carrier (TTC, SLC25A1) in brain mitochondria and astrocytes (Wadey et al., 2009)
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