If pancreatitis is suspected (severe abdominal pain, often radiating to the back), stop taking Mounjaro immediately and seek urgent medical advice
The fraction of weight lost as fat-free mass depends on baseline adiposity, age, sex, diet, protein intake, inactivity, resistance training, metabolic state, and the rate and duration of weight loss
Do not shake or vortex
Shared decision-making : If considering offlabel or prevention use, open discussion of uncertain benefit, possible side effects, cost, monitoring is essential
Studies have found that the best predictor for islet autoimmunity is genetic background, with predisposition caused by genetic susceptibility in multiple loci, including INS and the class I and II Major Histocompatibility Complex (MHC)/human leukocyte antigen (HLA) genes ( Figure 1 ) (6, 7)