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The structures were refined by combining manual adjustments in Coot v0.9.8.3 66 and ISOLDE 67 in UCSF ChimeraX 1.6.1 68 , followed by real-space refinement in PHENIX v1.20.1-4487 69 with Ramachandran, rotamer, torsion, and secondary structure restraints enforced
These include Brightens Complexion : by reducing the melanin in skin Reduces Signs of Ageing : By neutralising free radicals, glutathione helps minimise fine lines and wrinkles and supports collagen synthesis, improving skin firmness and elasticity Anti-inflammatory Effects : It helps soothe inflammatory skin conditions such as acne and eczema
Biochemically, ferroptosis involves iron dysregulation, ROS accumulation, mitochondrial dysfunction, glutathione (GSH) depletion, and lipid peroxidation (Liu et al., 2025)
