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OR 2 = 0.21 [95% CI 0.050.92], P 2 = 3.89 10 2 )

Preclinical results in murine models treated with GLP-1RAs suggest that the potential effects of semaglutide in AD may be exerted via impact on several AD-related pathophysiologic processes including neuroinflammatory pathways, vascular and BBB integrity, reduced synaptic loss, and neuroprotection [19, 21, 23,24,25,26, 46,47,48]

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