Patients evaluating their own eligibility should treat published BMI thresholds the same way: as the beginning of a clinical conversation, not the end of one
In a larger unsupervised clustering analysis ( n = 11,908), four sub-phenotypes were identified, broadly echoing this metabolicreproductive axis and showing substantial overlap with NIH-based subtyping frameworks (52), consistent with prior NIH subtype classifications and related work (50, 53)
Acknowledgements This study was supported by grants from the Chang Gung Memorial Foundation (CMRPG-5D0111, CMRPG2F0171, CMRPG2F0172, CMRPG2F0173, CMRPG-2G0361, CMRPG-2H0161, CRRPG2H0162, CMRPG-2J0261, CMRPG-2K0091, CORPG2N0141, CORPG2P0231, and CORPG2P0191), the Ministry of Science and Technology, Taiwan (104-2320-B-182A-013, 106-2314-B-182A-064, 107-2314-B-182A-138, 108-2320-B-182A-009-MY3, 108-2314-B-182A-027, 108-2321-B-182-003 and 109-2321-B-182-001) and the Taiwanese Ministry of Health and Welfare (MOHW110-TDU-B-212-124005, MOHW111-TDU-B-212-134005, MOHW112-TDU-B-212-144005)
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This can be particularly disheartening for those who have achieved their desired skin tone through supplementation