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A related formulation, Wegovy (also semaglutide but at higher doses), has separate MHRA approval specifically for weight management

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In general, researchers are advised to initiate trials with more conservative doses of about 0.5mg/daily and increase up to 2mg/daily only if needed, depending on subjects response

2.2 Information sources and search strategy A thorough literature search was carried out in PubMed, Embase, Cochrane Library, and Web of Science up to May 14, 2025

They also improve satiety , allowing you to feel full longer with smaller portions, which helps in reducing calorie intake