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Documented research applications include: Intranasal peptide absorption and mucosal bioavailability studies MC1R-mediated melanogenesis and pigmentation pathway research MC4R hypothalamic arousal and CNS neuromodulation investigations Comparative melanocortin receptor pharmacology (MC1RMC5R profiling) Energy homeostasis and appetite regulation via MC3R/MC4R models Route-of-administration pharmacokinetic comparison studies MC5R exocrine gland function and sebaceous biology research Cyclic peptide stability and degradation profiling in aqueous formulations Product Specifications Storage & Handling Store at 4C or below, protected from light

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All mice were housed in ventilated cages (with igloo and nestlets) in a barrier animal facility of the University of Texas Southwestern medical Center (UTSW) with a temperature- (22 C) and humidity- (55%) controlled environment, under a 12:12 h lightdark cycle

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