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Clinical trial data shows diarrhea rates of 19-23% across doses, with nausea remaining the predominant side effect at 24-31%

Note: Compounded medications are prepared based on specific patient needs or in the event of drug shortages and are not reviewed or approved by the FDA for safety or effectiveness

Despite its low potency at both receptors and less-certain in vivo activity at the GcgR, chronic OXM treatment decreased body weight and food intake in rodents when GLP-1R action was present [79,80,81]

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First, it involved a patient who already had neuropathy, raising the question of whether pre-existing nerve damage creates vulnerability to GLP-1-associated allodynia