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However, heterogeneity was high for the IV subgroup (I 2 = 52%), and the oral subgroup contained homogeneous studies (I 2 = 0%) (Table 3)

The therapeutic window sits between 0.51.5mg for most subjects, with optimal individual doses identified through systematic titration across 610 administrations

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Abstract The development of glucagon-like peptide 1 (GLP1) receptor agonists, including semaglutide and tirzepatide, has transformed the clinical management of overweight and obesity

Presented for research literature review only Benedict C (2022)