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GLP-1 medications are large peptide molecules-complex chains of amino acids with three-dimensional structures susceptible to degradation by stomach acid and digestive enzymes
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For diabetes (Ozempic), the dosing starts at 0.25 mg weekly for four weeks, increases to 0.5 mg, and can go up to 1.0 mg or 2.0 mg depending on glycemic needs
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Interestingly, Igl2 of SR18 also makes hydrophobic interactions with these two residues
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