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December 21, 2024: Saxenda Added to GLP-1 Consolidated Litigation

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Notably, the Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) trial, the first dedicated kidney outcome trial evaluating canagliflozin in people with type 2 diabetes mellitus and CKD, demonstrated a substantial reduction in the risk of kidney events [46]

The emergence of GIP antagonist conjugates (such as AMG-133 and Maridebart cafraglutide) further broadens the therapeutic landscape for patients with hyperphagic obesity or GLP-1 resistance