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Elevated GH stimulates liver production of IGF-1, the primary mediator of growth hormones anabolic and metabolic benefits

Some treatments like radiofrequency microneedling may require a series of three to four sessions for optimal results

This degradation, in turn, allows NF-B activity to increase, resulting in increased transcription of pro-inflammatory genes, including TNF-, IL-1, IL-6, and inducible nitric oxide synthase (iNOS) (Morgan and Liu, 2011)