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In clinical trials, participants indeed received counseling to improve diet and exercise (STEP 1 provided monthly individualized lifestyle counseling to all arms (source))
"There's up to 50% of individuals who go on to GLP-1 for weight management who stop taking the drug within 12 to 14 months for a variety of reasons, side effects gastrointestinal, behavioral, or otherwise
Antioxidant protection
Despite the above-mentioned disease burden, there is currently no available FDA- or EMA-approved medication for the disease, although numerous agents have been investigated in preclinical and clinical studies [5]
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