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Nutrient timing becomes less about optimization and more about survival

Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus , Lancet 1, 785789 Randle PJ, Newsholme EJ & Garland PJ (1964), Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles , Biochem J 93, 652665 Rebouche CJ, Engel AG

That's not a reason to automatically say no

So when we look at this, when we look at it through the lens, what you were asking me about with long Covid, with MCAS, etc