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In the Nile tilapia, the therapeutic mode of action of BP was detected on pathogen A
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Clinical data suggests dual therapy may offer additive glucose-lowering effects in specific type 2 diabetes cases, though individual response varies significantly
Moreover, existing studies mostly focus on the regulation of RA synovial cells (such as FLS) or macrophages by the cGAS-STING pathway, whereas this study, for the first time, clearly demonstrates the central role of the cGAS-STING-ferroptosis axis in RA chondrocytes, and reveals that GLP-1RAs exerted therapeutic effects on RA through a dual mechanism of directly inhibiting this axis and simultaneously promoting the M2 polarization of macrophages
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