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Plaque-targeted, proteolysis-resistant, activatable and MRI-visible nano-GLP-1 receptor agonist targets smooth muscle cell differentiation in atherosclerosis

Oliver, L., et al

The two peptides work on complementary pathways: CJC-1295 is a GHRH analogue that signals the pituitary gland to increase growth hormone output over time, and Ipamorelin is a selective ghrelin receptor agonist that triggers growth hormone pulses without significantly affecting cortisol or prolactin