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Activation of GLP-1R suppressed NTG-induced CGRP expression in the TNC CGRP is a widely recognized migraine-related mediator and is also involved in central sensitization in the TNC
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While SGLT2 inhibitors do promote modest weight loss (13 kg), their effect is less pronounced than that of GLP-1RA, and they have less impact on thyroid hormone absorption [42, 43]
1, 2 and 3 are available in Supplementary Data
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