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Orforglipron's unrestricted oral dosing and demonstrated superiority over oral semaglutide in ACHIEVE-3 position it as the preferred oral GLP-1 option for many patients
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Clinically, the Rog group exhibited more advanced tumor burden, with significantly large tumor sizes and higher metastasis rates because regorafenib is used as 2nd line treatment after sorafenib resistance in more progressed patients [47]
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