If you have any of the following, make sure to talk about it with your doctor: A history of pancreatitis Severe gastrointestinal diseases You are pregnant or breastfeeding A personal or family history of medullary thyroid cancer or multiple endocrine neoplasia If youre undergoing surgery, you may need to stop taking GLP-1 beforehand
During Salmonella Typhimurium infection, C16-carnitine localizes to regions of immune cell destruction, and C16-carnitine acts as a local immunoregulatory molecule that significantly interferes with host immune homeostasis by affecting the number and function of specific immune cell populations, such as T cells and B cells, suggesting that the accumulation of LCACs is part of the pathogen immune evasion strategy [60]
doi:10.1093/jn/132.4.636 Rosca MG, Lemieux H, Hoppel CL
Some research suggests it may increase GLP-1 production
AMG 133 (now known as maridebart cafraglutide) is an optimized GIPR/GLP-1R bispecific molecule engineered by conjugating a fully human monoclonal anti-human GIPR-Ab with two GLP-1 analogue agonist peptides using amino acid linkers