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Another limitation was that both studies had low numbers of participants, with the fewest in the groups with severe renal or hepatic impairment

There has been a lot of discontent among patients and rallying trying to reassess treatment within the UK, as well as to educate and research more on the ways in which PA is diagnosed

Mol Metab 2015;4:718-31.ArticlePubMedPMC 67

These findings are important because they support the manuscripts central argument that appetite suppression can constrain the nutritional substrate supply required for durable metabolic adaptation

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