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Description

PRMT8 controls the pluripotency and mesodermal fate of human embryonic stem cells by enhancing the PI3K/AKT/SOX2 axis

Nucleotide Res

The authors reported that AOD-9604 stimulated lipolysis in isolated adipocytes and that chronic daily treatment in obese Zucker rats produced reductions in body weight gain of more than 50% relative to untreated controls over the treatment period, without effects on insulin sensitivity or IGF-1 levels [3]