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Nature Metabolism

The sector experienced a dynamic mix of promising clinical trial results, expanded therapeutic indications beyond weight management, strategic partnerships, as well as emerging safety concerns and intensifying patent disputes with generics entering the fray

However, we cannot rule out the possibility that the structural variations we observed were caused by the non-native buffer conditions in our cryo-EM studies

These inflammatory signals further affect BBB transport systems, which regulate molecular exchanges between the blood and the brain

In addition, oxidative damage results in the aggregation of TDP-43, the major disease-associated protein involved in the pathogenesis of ALS (Moujalled et al., 2017