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This makes it a poor candidate for sustained research applications
doi: 10.2337/dc12-2006 29 FrasJPDaviesMJRosenstockJPrez ManghiFCFernndez LandLBergmanBKet al
The shorter working life of a 50mg vial is part of its advantage over the 100mg presentation, so avoid extending it unnecessarily
Interestingly, Fab 3F52 also blocked a short peptide agonist believed to engage primarily the transmembrane and extracellular loop region of GLP-1R, whereas functionality of an allosteric small-molecule agonist was not inhibited
That absence isn't evidence of a problem - it just means this article can't make a claim about public sentiment one way or the other
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