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The higher the GSH concentration, the greater the survival rate of oocytes after vitrification
It is considered to be the key mechanism of ROS-induced sperm damage and leads to Loss of sperm motility Abnormal sperm morphology Reduced capacity for oocyte penetration Infertility To protect sperm from damage, the body depends on powerful antioxidant enzymes in the body such as superoxide dismutase (SOD), catalase, and glutathione peroxidase/reductase (GPX/GRD)
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doi: 10.1038/s41392-023-01481-w, 18
The failure to demonstrate an increase in live-birth rate, despite an increase in pregnancy rates, is due to the very few RCTs specifically assessing the impact of AOX on live-birth rate
