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To move beyond supportive evidence, tirzepatide would probably need superiority on a prespecified CV endpoint in additional outcomes work such as SURMOUNT-MMO, plus consistent real-world data and meta-analyses that address differences in population and background therapy
Divino, V
In February 2025, the FDA removed semaglutide from the shortage list, which triggered a compliance deadline for compounders to wind down shortage-based production
Severe obesity was associated with additional costs of $3,097 per adult, while other studies have found a financial impact of around $2,500
Waist circumference shrinks noticeably
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