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[13] The first reaction of the carnitine shuttle is a two-step process catalyzed by a family of isozymes of acyl-CoA synthetase that are found in the outer mitochondrial membrane , where they promote the activation of fatty acids by forming a thioester bond between the fatty acid carboxyl group and the thiol group of coenzyme A to yield a fatty acylCoA

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Glutathione, the sole active ingredient, is a tripeptide composed of glutamine, cysteine, and glycine, and is recognized for its critical role in cellular defense against oxidative stress, as well as its involvement in numerous metabolic and detoxification pathways