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"Our study shows that patients treated for obesity with semaglutide or tirzepatide lost less weight on average in a regular clinical setting compared to what is observed in randomized clinical trials." Hamlet Gasoyan, PhD, Researcher, Cleveland Clinics Center for Value-Based Care Research Maintaining weight loss presents different challenges for each approach
Semaglutide can support real metabolic change, including reductions in visceral fat, as outlined in this blog post about semaglutide and exercise