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Because L-carnitine is absorbed via a specific sodium-dependent transporter in the small intestine (known as OCTN2) that can easily become saturated by large single doses, dividing the intake throughout the day maximizes overall intestinal absorption

The differences between the oxidation and reduction potentials of each metal is thought to have been advantageous to organism survival, allowing them to exist in environments with varying O 2 concentration and metal availability

10.1161/CIRCULATIONAHA.110.991869 134 Mano-OtagiriA.OhataH.Iwasaki-SekinoA.NemotoT.ShibasakiT

Plant Physiol 134:595604

Together, these elements create a holistic framework for health optimisation