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Two-thirds of enrollees had abnormal HbA1c (5.7-6.4%)

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Targeted DNA methylation by homology-directed repair in mammalian cells

R-lipoic acid is the better antioxidant due to its higher potency and bioavailability compared to alpha-lipoic acid, which is a mix of R-ALA and the less effective S-ALA

Treatment significantly reduced levels of pro-inflammatory cytokines including interleukin-1 (IL-1) and tumor necrosis factor- (TNF-) while increasing anti-inflammatory interleukin-10 (IL-10) expression