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260 mg/day for adolescents 15-17 years
The glucose-dependent nature of semaglutides insulin secretion generally results in a lower intrinsic risk of hypoglycemia compared to insulin or sulfonylureas, but the combination effect must be carefully managed
A study suggested also that the use of a BP-lowering central sympatholytic drug, moxonidine, might induce a small but significant weight loss, together with a reduction in blood pressure, triglycerides and fasting blood glucose (Chazova and Schlaich, 2013), though another study failed to demonstrate any impact on insulin sensitivity (Masajtis-Zagajewska et al., 2010)
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