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These distinctions stem from their mechanisms of action and the special outcomes

1,2 SORT: KEY RECOMMENDATIONS FOR PRACTICE Figure 1 In the United States and the United Kingdom, the prevalence of vitamin B 12 deficiency is approximately 6% in persons younger than 60 years, and nearly 20% in those older than 60 years

10.1111/apt.16451 54 KusunokiH.HarumaK.ManabeN.ImamuraH.KamadaT.ShiotaniA.et al (2012)

Unregulated versions are often synthesized in countries such as China and India, then shipped to the U.S

The 4 stages of B12 deficiency include (31): Stage 1: decreased levels of vitamin B12 in your blood Stage 2: low levels of vitamin B12 in your cells along with metabolic abnormalities Stage 3: neurological and psychological symptoms like anxiety, confusion, problems with balance, and others Stage 4: macrocytic anemia very large red blood cells (32) B12 deficiency can cause a variety of symptoms, including fatigue, headaches, depression, pale or yellow skin, mental impairment, and pain and inflammation in the mouth and tongue