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DATS inhibited bacterial lipopolysaccharide (LPS)-induced macrophage activation by limiting LPS binding to toll-like receptor 4 (TLR4) and blocking the upregulation of TLR4 and TLR4-associated molecule MyoD88 expression (37)

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Specifically, researchers commented that NAC exhibits strong potential for the protection of the diabetic heart at risk of myocardial infarction through inhibition of oxidative stress... Further, a 2019 review article in Pharmacological Research discussed evidence demonstrating NAC could help improve insulin sensitivity in those with insulin resistance, prediabetes

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Tubes containing PBS alone served as unstimulated controls, and pokeweed mitogen was used as a positive control to verify cell viability and responsiveness