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American Medical Association: What Doctors Wish Patients Knew About Anti-Obesity Medication Centers for Disease Control and Prevention: Steps for Losing Weight Harvard Health Publishing: GLP-1 Diabetes and Weight-Loss Drug Side Effects: Ozempic Face and More Keck Medicine of USC: What Doctors Think About Prescribing Wegovy and Ozempic for Weight Loss Rodriguez PJ et al

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How GLP-1s Work in the Body Slow gastric emptying (food stays in the stomach longer) Increase satiety signals to the brain Reduce appetite and overall intake Improve insulin response and glycemic control While these effects support metabolic health, slower digestion is also what sets the stage for GI symptoms, including reflux. Digestive Impact of GLP-1s: What the Research Shows Increased Upper GI Symptoms One of the most consistent findings across GLP-1 clinical trials is the high rate of gastrointestinal side effects

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